Alumni Feature: From lab bench to boardroom, Danielle Pascoli is giving waste a second life

Danielle Pascoli in a graduation cap and gown
Danielle Pascoli holding nanocellulose film made from agricultural wastes.

Where some see waste, SEFS alumna Danielle Pascoli sees possibility. That perspective has led her from looking for higher-value uses for plant waste during her PhD to becoming the sole founder of an innovative nanofiber company in the last year.

As an undergraduate student in her home country of Brazil, Danielle was a biochemical engineering major when she joined a research project using waste material from sugarcane industry to make biofuels.

“That was the first time I did anything hands-on, and I remember my mind was blown. You’re taking trash and waste and you’re making a valuable product out of it. I was so in love with that idea that I knew I wanted to keep doing this for my career,” said Danielle.

Years later, Danielle joined the Bioresource Science and Engineering program at the UW School of Environmental and Forest Sciences (SEFS) to work with Professors Renata Bura and Rick Gustafson on biofuel research for her master’s degree. With a growing interest in working with longer-lasting materials, Danielle turned her focus to biomaterials, such as nanocellulose, for her PhD studies. Nanocellulose is a natural biopolymer made from plant materials that has unique properties, such as reinforcing and lightweighing, and can be used to create enhanced and more sustainable materials in many industries.

From cosmetics, electronics, and sensors, to packaging, plastic, and cement, nanocellulose has an array of applications. But the nanofibers currently on the market are made with expensive wood pulp materials through processes with a high environmental and economic cost, which limits their production on a large scale. Danielle and her advisors set out to find a better alternative.

“We wanted to solve that problem. That’s how it all started,” said Danielle. Using different types of waste from agricultural residues, invasive plant species, and industrial hemp, they started developing a low-cost process to produce nanocellulose. The project began with Washington State funding Prof. Gustafson and Bura’s effort to develop sustainable biobased industries for Lewis County – a region of the state that is aggressively developing its industrial base. One of the industries was the production of nanocellulose, and in the course of the research, it was discovered that reed canary grass, a widespread invasive species in the state that overtakes native plants and harms biodiversity, is an excellent feedstock for nanocellulose production. The use of an invasive species to produce a very high-value product is so compelling that Gustafson and Bura have since been awarded an additional $1 million from Washington State to continue this research.

Not only did their process work, the nanocellulose they created vastly improved the materials it was added to. When incorporated into biodegradable plastic, the material becomes stronger, tougher, and more flexible. What’s more, the process was by far more cost-effective than any existing system and could be adapted to a range of waste materials.

Danielle Pascoli and Professor Renata Bura
Danielle and Prof. Renata Bura in 2022.

In the last year of her PhD program, Danielle was mainly focused on testing the materials in front of her, and her impending graduation timeline. That changed when she attended a presentation on the Activate Fellowship program during a conference. Activate focuses on helping scientists turn their technologies into products, and bring real solutions to life through commercial enterprises. Both of Danielle’s advisors immediately encouraged her to apply, despite her initial hesitations.

“I was focused on graduating. That was my last year, I had my thesis defense coming up. I was like, ‘I’m worried about defending, I’m not worried about creating a company right now,’” said Danielle. But over the course of a few weeks, her advisors helped her see her own potential as an entrepreneur and leader, so she decided to submit an application based on the technology she developed at the UW.

The fellowship kicked off a whirlwind journey that led Danielle to defend her thesis, complete her PhD, move to a different state, and start a company on her own in the span of the summer of 2022. She faced a massive transition from the academic world and soon found the NSF’s Innovation Corps (I-Corps) program to help build her entrepreneurial skills and confidence. The I-Corps program is an immersive, entrepreneurial training program that facilitates scientists along the transformation toward commercialization.

In the year since Danielle launched VERDE Nanomaterials, she has tackled a dramatic learning curve. From finding funders and market testing products to navigating all the bureaucratic red tape that accompanies running a business, she was grateful for the continued support of her former advisors and fellows cohort.

“It wasn’t something that I was born with, thinking ‘I’m going to create a company. I’m an entrepreneur.’ It really grew on me over time,” said Danielle.

Danielle Pascoli poses with a poster
Danielle Pascoli at a startup showcase at Climate Tech Cocktails at UC Berkeley (2023).

Her first year as a company founder was far from easy. She had to learn how not to think like a scientist 100% of the time, and start seeing the world from a business perspective. She learned that just having really cool technology is not enough. Figuring out what value your technology brings to the world is key to success.

Now, Danielle is building a vision for her budding company. Currently, she’s testing materials to find out what type of product will be most cost-effective, in demand, and effective to produce as her first prototype. In the coming year, Danielle plans to hire her first employee.

Having mentors that helped her take the leap out of the lab and into creating real-world solutions has allowed her to go farther than she ever anticipated.

“I am 100% sure that if I weren’t at SEFS, working with the people I worked with, I would never be doing what I’m doing right now. It felt like I wasn’t trying anything by myself. I really had a network of support that was there, saying ‘you can do it,’” said Danielle.


Bioresource Science and Engineering Students win the Spark Award at Environmental Innovation Challenge

A team from the SEFS Bioresource Science and Engineering program received a $1,000 Spark Award at the 2023 UW Alaska Environmental Innovation Challenge, an annual competition inspiring university students solve environmental and cleantech problems.

three people pose together outdoors holding an envelope
Green Grab, the winning BSE team

The Green Grab team was a top finalist out of 21 groups selected to showcase their solutions to judges in March. They developed a compostable and recyclable food tray made from Reed Canary Grass, an invasive plant, and nanocellulose, a light solid substance obtained from plant matter produced with a proprietary process developed at SEFS. The trays present an alternative to plastic or existing molded-fiber products as they are made without PFAS (per- and polyfluoroalkyl substances), a large, complex group of synthetic chemicals that accumulate over time in the human body and the environment. Some compostable containers contain PFAS to strengthen the material, leading to issues with PFAS contamination in compost piles.

Congratulations to Green Grab!


Professor Tobin Awarded Powell Grant to Study Insect Invasiveness

Last month, Professor Patrick Tobin and a team of researchers were awarded an innovative grant from the John Wesley Powell Center for Analysis and Synthesis in Fort Collins, Colo.: “Predicting the next high-impact insect invasion: Elucidating traits and factors determining the risk of introduced herbivorous insects on North American native plants.”

This fall, entering his second full year on the SEFS faculty, Tobin welcomed four new grad students to his newly refurbished “Disturbance Ecology Lab.”
This fall, entering his second full year on the SEFS faculty, Tobin welcomed four new grad students to his newly refurbished “Disturbance Ecology Lab.”

Powell grants are somewhat unique in that they don’t fund new data collection and research, but rather “Working Groups” that mine and synthesize existing data sets to discover overarching trends and insights. For Tobin’s group, they wanted to search for broad patterns in what drives invasiveness on a continental scale. All non-native species initially lack natural predators, he says, and they all generally feed on host plants that haven’t adapted to them. Yet out of 100 introduced insects, there are probably only three or four that become high-impact pests—like the emerald ash borer (Agrilus planipennis)—that are dangerous enough to cause cascading changes to ecosystems. So what’s different about the other 90 to 95 percent of non-native species? What separates the really bad invasive species from the basically benign?

“I’ve dedicated my professional career to this question,” says Tobin, “so I’m excited to have this working group and the resources to really dive into it.”

The ultimate goal of this research is to develop a framework to help predict and prioritize strategies against future insect threats in the United States—with direct applications to invasive species management and risk assessment around the country and world.

The Working Group
When you submit a proposal to the Powell Center, you pitch a project and also a proposed participant list to make up a working group of about 15 scientists. The idea is to bring together a diverse set of specialties and backgrounds to explore an issue as comprehensively as possible. So Tobin’s group includes three co-investigators—Professor Daniel Herms from Ohio State University, Professor Travis Marsico from Arkansas State University, and Dr. Kathryn Thomas, a plant ecologist with the U.S. Geological Survey—along with a host of other experts from 12 different universities, ranging from chemical ecologists to population geneticists to forest ecologists.

Emerald ash borer (Agrilus planipennis) larva.
Emerald ash borer larva.

Their group had submitted this concept two times previously before finally securing the grant—one of four awarded out of 50 proposals in 2015. “We almost didn’t pitch it the third year,” he says, “but we decided to try one more time. You have to be persistent and keep improving your proposal, and you can’t get frustrated. Last year, we had the dubious honor of being the top-ranked proposal not funded. This year we’re the top-ranked proposal overall. Sometimes in the grant process, it’s just a matter of convincing them it’s a good idea, and it can take a couple years to do that.”

The award will cover travel expenses for the researchers to make three weeklong visits to meet as a group at the U.S. Geological Survey’s Fort Collins Science Center, where they will have full access to the facility’s computational, data manipulation and data management resources. They will have plenty of homework in-between these visits, as well, and the grant also includes up to $100,000 for a postdoc to help guide the project for two years.

Tobin says the postdoc, who will be working directly with him and based at SEFS, will be crucial to the success of the project. “The beauty of these working groups is that they really want you to get things done,” he says. “It’s a great opportunity for a postdoc to work with this diverse group of people, and they really get to pump out a lot of papers.”

The group’s plan is to meet this coming June for the first time, and Tobin will start looking this fall for a quantitative ecologist to fill the postpoc position. He has also recruited an undergrad at SEFS to help as part of a capstone project.

Photos © Patrick Tobin.

Cactus moth (now caterpillar) Cactoblastis cactorum.
Cactus moth larvae (Cactoblastis cactorum).